Product Overview
Zoliflodacin | TQ0063 | TargetMol Chemicals
CAS: 1620458-09-4
Smiles: [H][C@]12[C@H](C)O[C@H](C)CN1c1c(CC22C(=O)NC(=O)NC2=O)cc2c(noc2c1F)N1[C@@H](C)COC1=O
Formula: C22H22FN5O7
Pathway: Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Microbiology/Virology
Target: DNA gyrase|||DNA/RNA Synthesis|||Topoisomerase|||Antibacterial
Receptor: N/A
Bioactivity: Zoliflodacin (ETX0914, AZD0914) is a new bacterial DNA gyrase/topoisomerase inhibitor. Zoliflodacin has potent in vitro antibacterial activity against Gram-positive and Gram-negative organisms, including S. aureus (MIC90: 0.25 μg/mL).
Molecular Weight: 487, 444