Product Overview
11Beta-hydroxyprogesterone | TCA2511 | TargetMol Chemicals
CAS: 600-57-7
Smiles: CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)C3[C@@H](O)C[C@]12C
Formula: C21H30O3
Pathway: Membrane transporter/Ion channel
Target: Sodium Channel
Receptor: N/A
Bioactivity: The progesterone derivatives 11 alpha- and 11 beta-hydroxyprogesterone are potent inhibitors of 11 beta-hydroxysteroid dehydrogenase (isoforms 1 and 2) in vitro and can confer mineralocorticoid activity on corticosterone in the rat in vivo. 11beta-Hydroxyprogesterone acts as a mineralocorticoid agonist in stimulating Na+ absorption in mammalian principal cortical collecting duct cells.
Molecular Weight: 330, 46
