Product Overview
BMS-P5 free base | T22277L | TargetMol Chemicals
CAS: 1550371-22-6
Smiles: COc1cc(cc2nc(-c3cc4cccnc4n3CC3CC3)n(C)c12)C(=O)N1C[C@H](N)CC[C@@H]1C
Formula: C27H32N6O2
Pathway: Chromatin/Epigenetic
Target: PAD
Receptor: N/A
Bioactivity: BMS-P5 free base is a specific and orally active peptidylarginine deiminase 4 (PAD4) inhibitor. BMS-P5 Blocks Formation of Neutrophil Extracellular Traps and Delays Progression of Multiple Myeloma. Administration of BMS-P5 to multiple myeloma-bearing mice delays appearance of symptoms and disease progression Targeting PAD4 may be beneficial for treatment of multiple myeloma.
Molecular Weight: 472, 593
