Product Overview
Cabozantinib hydrochloride | T5164 | TargetMol Chemicals
CAS: 1817759-42-4
Smiles: Cl.COc1cc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3)c2cc1OC
Formula: C28H25ClFN3O5
Pathway: Angiogenesis|||Metabolism|||Tyrosine Kinase/Adaptors
Target: VEGFR|||FLT|||c-Met/HGFR|||TAM Receptor|||c-Kit|||ROR
Receptor: N/A
Bioactivity: Cabozantinib (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6 nM).
Molecular Weight: 537, 96
