Product Overview
Cabozantinib | T2586 | TargetMol Chemicals
CAS: 849217-68-1
Smiles: COc1cc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3)c2cc1OC
Formula: C28H24FN3O5
Pathway: Angiogenesis|||Apoptosis|||Tyrosine Kinase/Adaptors
Target: Apoptosis|||VEGFR|||FLT|||c-Met/HGFR|||c-RET|||TAM Receptor|||c-Kit
Receptor: N/A
Bioactivity: Cabozantinib (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50s: 0.035, 1.3, 4.6, 7 and 11.3 nM).
Molecular Weight: 501, 514
