Product Overview
Clozapine | T0455 | TargetMol Chemicals
CAS: 5786-21-0
Smiles: CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12
Formula: C18H19ClN4
Pathway: GPCR/G Protein|||Neuroscience
Target: Dopamine Receptor|||Adrenergic Receptor|||AChR
Receptor: N/A
Bioactivity: Clozapine is a tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacological profile. Clozapine is a serotonin antagonist, with strong binding to 5-HT 2A/2C receptor subtype. It also displays strong affinity to several dopaminergic receptors, but shows only weak antagonism at the dopamine D2 receptor, a receptor commonly thought to modulate neuroleptic activity.
Molecular Weight: 326, 83
