Product Overview
Cucurbitacin IIA | T3S1471 | TargetMol Chemicals
CAS: 58546-34-2
Smiles: CC(=O)OC(C)(C)CCC(=O)[C@](C)(O)[C@H]1[C@H](O)C[C@@]2(C)[C@@H]3CC=C4[C@@H](C[C@H](O)[C@@H](O)C4(C)C)[C@]3(C)C(=O)C[C@]12C
Formula: C32H50O8
Pathway: Apoptosis
Target: Apoptosis|||Survivin
Receptor: N/A
Bioactivity: 1. Cucurbitacin IIA can induce apoptosis and enhance autophagy, contributes to the anti-inflammatory activity of Cucurbitacin IIA against inflammation-related diseases. 2. Cucurbitacin IIA is a novel class of anti-cancer drug in suppression of cancer cell expansion by disrupting the actin cytoskeleton and directing the cell to undergo PARP-mediated apoptosis through the inhibition of survivin downstream of JAK2/STAT3.
Molecular Weight: 562, 744
