Mouse Anti-Hla mAb (8B7)
Polypeptide sequence of Staphylococcus alphahemolysin targeting the N terminus of the mature toxin.
Mouse monoclonal antibody (mAb) reactive to full length Staphylococcus aureus alpha-hemolysin (alpha-toxin). The antibody detects the antigen produced by S. aureus strains in Western Blotting and ELISA and neutralizes the hemolytic activity of the toxin.
100 µg is supplied in PBS at a concentration of 1.68 mg/mL.
Antibody is purified using immobilized protein A.
The antibody can be used for detection and neutralization of alpha-toxin produced by virulent strains of S. aureus.
Optimal use dilution should be determined for each individual application.
This antibody does not appear to cross react with Staphylococcal enterotoxin B (SEB), rLukS-PV or rLukF-PV based on historical ELISA data. As with most antibodies, this antibody interacts with Protein A in S. aureus culture supernatant via the Fc region.
2-3 weeks +4oC, -20◦C long term.