Product Overview
Pazopanib Hydrochloride | T6930 | TargetMol Chemicals
CAS: 635702-64-6
Smiles: Cl.CN(c1ccc2c(C)n(C)nc2c1)c1ccnc(Nc2ccc(C)c(c2)S(N)(=O)=O)n1
Formula: C21H24ClN7O2S
Pathway: Angiogenesis|||Autophagy|||Tyrosine Kinase/Adaptors
Target: c-Fms|||VEGFR|||FGFR|||PDGFR|||c-Kit|||Autophagy
Receptor: N/A
Bioactivity: Pazopanib HCl (GW786034 HCl) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM in cell-free assays, respectively.
Molecular Weight: 473, 98
