Product Overview
Pazopanib | T0097L | TargetMol Chemicals
CAS: 444731-52-6
Smiles: CN(c1ccc2c(C)n(C)nc2c1)c1ccnc(Nc2ccc(C)c(c2)S(N)(=O)=O)n1
Formula: C21H23N7O2S
Pathway: Angiogenesis|||Autophagy|||Tyrosine Kinase/Adaptors
Target: VEGFR|||FGFR|||PDGFR|||c-Kit|||Autophagy
Receptor: N/A
Bioactivity: Pazopanib, a small molecule inhibitor, inhibits multiple protein tyrosine kinases with potential antineoplastic activity. Pazopanib selectively inhibits VEGFR-1, -2 and -3, c-kit and PDGF-R, which may result in inhibition of angiogenesis in tumors in which these receptors are upregulated.
Molecular Weight: 437, 52
