Product Overview
(S)-crizotinib | T6357 | TargetMol Chemicals
CAS: 1374356-45-2
Smiles: C[C@H](Oc1cc(cnc1N)-c1cnn(c1)C1CCNCC1)c1c(Cl)ccc(F)c1Cl
Formula: C21H22Cl2FN5O
Pathway: Apoptosis|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair
Target: Apoptosis|||DNA/RNA Synthesis|||MTH1
Receptor: N/A
Bioactivity: (S)-crizotinib（IC50 of 72 nM）, an effective MTH1 (NUDT1) inhibitor, is the (S)-enantiomer of crizotinib.
Molecular Weight: 450, 34
