Product Overview
Spexin acetate(1370290-58-6 free base) | TP1930L1 | TargetMol Chemicals
CAS: TP1930L1
Smiles: CC(O)=O.O=C(O)CC[C@@H](C(N)=O)NC([C@H](C)NC(CNC([C@H](CCCCN)NC([C@H](CC(C)C)NC([C@H](CC1=CC=C(O)C=C1)NC([C@H](CC(C)C)NC([C@H](CCSC)NC([C@H](C)NC([C@H](CCC(N)=O)NC([C@H]2N(C([C@H]([C@H](O)C)NC([C@H](CC3=CNC4=C3C=CC=C4)NC([C@H](CC(N)=O)N)=O)=O)=O)CCC2)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Formula: C76H117N19O22S
Pathway: GPCR/G Protein|||Neuroscience
Target: Neuropeptide Y Receptor
Receptor: N/A
Bioactivity: Spexin acetate is a potent galanin receptor 2/3 (GAL2/GAL3) agonist (EC50 values are 45.7 and 112.2 nM, respectively). Exhibits no significant activity at galanin receptor 1. Endogenous satiety-inducing peptide; inhibits long chain fatty acid uptake by adipocytes and decreases food consumption in diet-induced obese mice and rats. Attenuates LH secretion in goldfish. Exhibits anxiolytic effects in vivo.
Molecular Weight: 1680, 94
